100.3% Raw Arbutin Powder for skin-lightening

Arbutin
MF:C12H16O7
MW:272.25
CAS:497-76-7
Appearance:white powder
Purity:100.3%

Arbutin is a glycoside; a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos. It inhibits tyrosinase and thus prevents the formation of melanin. Arbutin is therefore used as a skin-lightening agent. Arbutin is found in wheat, and is concentrated in pear skins. It is also found in Bergenia crassifolia.Arbutin was also produced by an in vitro culture of Schisandra chinensis.
Use Level:
Recommendatory amount of usage: 1-10%

99.96% Raw alpha-Arbutin Powder

alpha-Arbutin
MF:C12H17O7
MW:272.25
CAS:84380-01-8
Appearance:white powder
Purity:99.96%

Alpha-Arbutin is the more effective, faster and safer approach to skin lightening. It lightens the color of the skin more efficiently and effectively than do existing single components

Alpha-arbutin blocks epidermal melanin biosynthesis by inhibiting enzymatic oxidation of Tyrosine and Dopa. It acts faster and more efficient than do existing single components.

Function:
Promotes lightening and an even skin tone on all skin types.
Minimizes liver spots.
Can reduce the degree of skin tanning after UV exposure.

Cosmetic application:
All degrees of skin lightening.

 

 

 

CoQ10 (CoEnzyme Q10) /Ubidecarenone For Skin Care

CoQ10 (CoEnzyme Q10) For Skin Care
MF:C59H90O4
MW:863.34
CAS:303-98-0
Appearance:white powder
Purity:99%

Coenzyme Q10 is a molecule naturally involved in energy metabolism in all human cells. Among its many benefits, the antioxidant properties are the most researched. This molecule can prevent oxidation damage to water-insoluble molecules, DNA mutations, collagen synthesis decrease, pigmentation, inflammation and other adverse effects associated with UV exposure and ageing. In combination with vitamin E or other antioxidants, an exceedingly strong antioxidative effect can be achieved. Furthermore, coenzyme Q10 has a unique capability to protect against infrared A radiation, which is also found in sunlight. The promotion of collagen synthesis makes this coenzyme useful in treating ageing-associated skin changes, such as wrinkle appearance. Finally, its anti-inflammatory effect is beneficial not only for UV-damaged skin, but also for wound healing support.

Key benefits of Coenzyme Q10 in skin care:
Sun damage protection
Antioxidant
Increase cellular energy production
Stimulate collagen production
Lightening & brightening
Sun damage repair
Reduce fine lines & wrinkles
Wound healing support
Anti-inflammatory

 

4-(alpha-Methylbenzyl)resorcinol

4-(alpha-Methylbenzyl)resorcinol
MF:C14H14O2
MW:214.25976
CAS:85-27-8
Appearance:white powder
Purity:99%

99.9% 3-O-Ethyl-L-ascorbic acid /Ethyl Ascorbic Acid Raw Powder

3-O-Ethyl-L-ascorbic acid /Ethyl Ascorbic Acid
MF:C8H12O6
MW:204.18
CAS:86404-04-8
Appearance:Yellow crystalline powder
Purity:99.9%

3-O-Ethyl-L-Ascorbic Acid, or Ethyl Ascorbic Acid is a molecule produced by modifying Ascorbic Acid, commonly known as Vitamin C. This modification is done to increase the molecule’s stability and enhance its transport through skin, as pure Vitamin C is easily degraded. In the body, the modifying group is removed and Vitamin C is restored in its natural form. Thus, Ethyl Ascorbic Acid retains the benefits of Vitamin C, such as antioxidant activity. Furthermore, it is even more potent in reducing skin darkening after UV exposure. It even has some additional effects, not observed in pure Ascorbic Acid, such as promoting nerve cell growth or reducing chemotherapy damage. Finally, the slower release also ensures that no toxic effects are observed when using this Vitamin C derivative.

Character:
Ethyl Ascorbic Acid is one kind of Vitamin C ramification. It dissolves in both oil base and water base. It can easy penetrate horniness to reach the dermis, and by the action of enzyme it decompounds and releases free Vitamin C.
Application:
It can be used in whitening or anti-aging cosmetics such as gel, essence, latex and creams.

Key benefits of Ethyl ascorbic acid in skin care:
Stimulate collagen production
Lightening & brightening
Treat hyperpigmentation
Sun damage protection

Dosage:
0.5~2.0%

99.7% BP standard Tranexamic Acid

Tranexamic Acid
MF:C8H15NO2
MW:157.21
CAS:1197-18-8
Appearance:White crystalline powder
Purity:99.7%
Standard:BP standard

Functions
1.Whitening and prevent pigmentation
• Reduce or remove the pigmentation of skin
Prevent and/or treat pigmentations such as chloasmas, freckles, sunburn, dark skin and melanoderma caused by a drug such as steroid
• Minimize dark spot area due to sun exposure.
• Anti-inflammation
Act on the chronic mild inflammatory condition at the sites of spots, to suppress melanocyte activation

2.Inhibit or improve skin roughness
Restore damaged skin caused by UVA/UVB, pollution or other environmental factors.
Mechanism of whitening skin
• Block melanin formation path induced by ultraviolet rays
• Prevent melanin accumulation
• Decreases melanocyte tyrosinase activity by preventing the binding of plasminogen to the keratinocytes, which results in reduction of prostaglandins and arachidonic acid, which are inflammatory mediators involved in melanogenesis.

3.Synergistic effects with other whitening ingredients:
Tranexamic acid produces good synergistic effect when combined with ascorbic acid or its derivatives such as magnesium ascorbyl phosphate, 3-O-ethyl ascorbic acid, disodium adenosine triphophate, escinol (deacylated product of escin under hydrolysis by sodium methylate), L-cysteine. Penetration enhancers helps the transdermic absorption of tranexamic acid into spots.

Application
Tranexamic acid is suitable to all kinds of skin for removing pigmentation, whitening skin and reducing spots, such as:
•Pigmentation after sun exposure
•Dark spots
•Sensitive skin
•Acne and inflammation
•Postoperative care after laser, pulsed light treatment

99.9% USP standard Tretinoin powder

Tretinoin
MF:C20H28O2
MW:300.44
CAS:302-79-4
Appearance:Yellow crystalline powder
Purity:99.9%
Standard:USP standard

Tretinoin, also known as all-trans retinoic acid (ATRA), is medication used for the treatment of acne and acute promyelocytic leukemia. For acne it is applied to the skin as a cream or ointment.For leukemia it is taken by mouth for up to three months.

Tretinoin is most commonly used to treat acne. It is also used off-label to treat and reduce the appearance of stretch marks by increasing collagen production in the dermis.

Action and Application
1. Treatment of acne
2. Reduce pigmentation
Inhibit tyrosinase induction, interfere with pigment transfer, accelerate epidermal turnover, disperse pigment granules within keratinocytes. Act as penetration enhancers when used with other lightening agents.
3. Treatment of melasma

99% Raw Glutathione Powder for Whitening

99% Raw Glutathione Powder for Whitening
CAS:70-18-8
Einecs: 200-725-4
Mf: C10h17n3o6s
Purity:99%
Appearance:white powder
Grade:Medical grade and food grade
Standard:USP standard

Glutathione (GSH) is an important antioxidant in plants, animals, fungi, and some bacteria and archaea, preventing damage to important cellular components caused by reactive oxygen species such as free radicals, peroxides, lipid peroxides and heavy metals. It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side-chain and the amine group of cysteine (which is attached by normal peptide linkage to a glycine).
Glutathione is not an essential nutrient for humans, since it can be biosynthesized in the body from the amino acids L-cysteine, L-glutamic acid, and glycine. The sulfhydryl group (SH) of cysteine serves as a proton donor and is responsible for its biological activity. Cysteine is the rate-limiting factor in cellular glutathione biosynthesis, since this amino acid is relatively rare in foods.

Usage:
Glutathione has multiple functions:
1:It is one of the major endogenous antioxidant produced by the cells, participating directly in the neutralization of free radicals and reactive oxygen compounds, as well as maintaining exogenous antioxidants such as vitamins C and E in their reduced (active) forms.
2:Regulation of the nitric oxide cycle is critical for life, but can be problematic if unregulated.
3:It is used in metabolic and biochemical reactions such as DNA synthesis and repair, protein synthesis, prostaglandin synthesis, amino acid transport, and enzyme activation. Thus, every system in the body can be affected by the state of the glutathione system, especially the immune system, the nervous system, the gastrointestinal system, and the lungs
4:It has a vital function in iron metabolism. Yeast cells depleted of or containing toxic levels of GSH show an intense iron starvation-like response and impairment of the activity of extramitochondrial ISC enzymes, followed by death
5:It has roles in progression of the cell cycle, including cell death.[GSH levels regulate of redox changes to nuclear proteins necessary for the initiation of cell differentiation. Differences in GSH levels also determine the expressed mode of cell death, being either apoptosis or cell necrosis.

Chinese EGCG Raw Powder

EGCG
MF:C22H18O11
MW:458.37
CAS:989-51-5
Purity:98%
Appearance:white powder

The benefits:
Anti-cancer:
EGCG appears to have powerful antioxidant effects against free radicals, unstable molecules that can damage healthy cells and cause cancer as a result. According to a paper published in “Biochemical Pharmacology” in 2011, EGCG has proven to inhibit tumor growth in a variety of test-tube studies involving cancer of the stomach, lungs, liver, breast and colon. In addition, it promotes the death of cancer cells. The authors concluded that EGCG presents a promising cancer treatment, either alone or with other therapies.
Brain Health:
In an animal study published in a 2012 issue of “Molecular Nutrition & Food Research,” researchers looked at the potential of EGCG to enhance brain function. Specifically, they studied the effects of the polyphenol on the generation of neurons in the hippocampus, the area of the brain where memories are formed and is most affected by diseases such as Alzheimer’s and Parkinson’s. The research team found that the EGCG in green tea promotes neurogenesis — neuron creation — in the hippocampus of adult mice, thus improving cognitive function.
Heart Health:
The potential effects of EGCG for preventing heart disease, hypertension and stroke have also come under scrutiny. In a review published in 2007 in the “Journal of the American College of Nutrition,” Swen Wolfram, Ph.D., outlined the many cardiovascular benefits associated with green tea. In particular, he noted positive results in large human studies in which participants consumed 5 to 6 cups a day containing 200 to 300 milligrams of EGCG.
Weight Loss:
Obtaining EGCG from green tea also promotes weight loss by promoting diet-induced thermogenesis and fat oxidation. A study published in the December 1999 issue of the “American Journal of Clinical Nutrition” tested 24-hour energy expenditure in humans. One group of participants received 90 milligrams of EGCG and 50 milligrams of caffeine from green tea extract, the second got the caffeine dose only and the third received a placebo. These were taken with three meals. Only the EGCG and caffeine group experienced significant energy expenditure, leading the researchers to conclude that the polyphenol has greater potential than the caffeine in green tea for promoting weight loss.

98.06% Astaxanthin Powder

Astaxanthin
MF:C40H52O4
MW:596.84
CAS:472-61-7
Purity:98.06%
Appearance:violet-red crystals powder

Astaxanthin is a keto-carotenoid.It belongs to a larger class of chemical compounds known as terpenes (in Asthaxanthin’s case, a tetraterpenoid); terpenes are built from five carbon precursors; isopentenyl diphosphate (or IPP) and dimethylallyl diphosphate (or DMAPP). Astaxanthin is classified as a xanthophyll (originally derived from a word meaning “yellow leaves” since yellow plant leaf pigments were the first recognized of the xanthophyll family of carotenoids), but currently employed to describe carotenoid compounds that have oxygen-containing moities, hydroxyl (-OH) or ketone (C=O), such as zeaxanthin and canthaxanthin. Indeed, astaxanthin is a metabolite of zeaxanthin and/or canthaxanthin, containing both hydroxyl and ketone functional groups.

astaxanthin, its vast ability to protect and promote healthy immune functioning, reduce cancer risk, mitigate the impact of diabesity, protect heart muscle and blood vessels, slow brain aging, and support eye health.

While astaxanthin is a natural dietary component, it can also be used as a food supplement. The supplement is intended for human, animal, and aquaculture consumption.